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Weekly

Nature Briefing: Translational Research

Top stories in biotechnology, drug discovery, and pharma, highlighting AI-enabled milestones like clinical trials for AI-discovered drugs targeting idiopathic pulmonary fibrosis and regulatory challenges in AI therapeutics.

Nature Medicine

AI

Biotechnology & Medicine

Clinical Trials

Annual

PP405 Molecule: Stem Cell Reactivator for Pattern Baldness

UCLA researchers developed PP405, a topical molecule that inhibits the SCUBE3 protein to 'wake up' dormant hair follicle stem cells, promoting regrowth. Phase 1 trials showed safety and follicle activation in humans within a week; Phase 3 starts in 2026. Effective in mice for full reversal, with potential to regrow hair on scarred scalps.

UCLA Broad Stem Cell Research Center & Pelage Pharmaceuticals

Longevity Escape Velocity

Clinical Trials